Comprehensive Problem Gambling Act of 2010 - Amends the Public Health Service Act to require the Secretary of Health and Human Services (HHS), acting through the Administrator of the Substance Abuse and Mental Health Services Administration, to: (1) establish and implement programs for the identification, prevention, and treatment of pathological and other problem gambling; (2) carry out a national campaign to increase knowledge and raise awareness of problem gambling; (3) establish and implement a national program of research on problem gambling; and (4) make grants to states, local and tribal governments, and nonprofit agencies to provide comprehensive services with respect to treatment and prevention of, and education about, problem gambling.
Authorizes the Secretary, in carrying out the national campaign, to: (1) administer and coordinate the voluntary donation of resources to assist in implementing new programs and augmenting and supporting existing national campaigns; and (2) encourage media outlets to provide information aimed at preventing problem gambling. Requires the Secretary to target radio and television audiences of events including sporting and gambling events.
Directs the Secretary to develop a treatment improvement protocol for problem gambling.