Teen Pregnancy Prevention, Responsibility, and Opportunity Act of 2005 - Authorizes the Secretary of Health and Human Services to make grants to: (1) local educational agencies, state and local public health agencies, and nonprofit private entities for projects to provide education on preventing teen pregnancies; and (2) public or nonprofit private entities for demonstrating innovative approaches to prevent teen pregnancies.
Reauthorizes appropriations for: (1) 21st Century Community Learning Centers and the Carol M. White physical education program, under the Elementary and Secondary Education Act of 1965; and (2) TRIO programs and GEARUP, under the Higher Education Act of 1965.