Coastal Jobs Creation Act of 2010 - Directs the Secretary of Commerce to implement a Coastal Jobs Creation Grant Program which shall include research and programs regarding: (1) recreational and commercial fisheries management: (2) essential fish habitats; (3) fishery and marine mammal stock assessments; (4) training and deployment of observers under the Magnuson-Stevens Fishery Conservation and Management Act; (5) conservation of ocean and coastal resources; (6) waterfront and port redevelopment; (7) coral reef ecosystem conservation; (8) improvement of coastal and ocean observation technologies; (9) bycatch reduction; and (10) preventing the occurrence and adverse impacts of marine debris on the marine environment and navigation safety.