Teacher Acculturation Act of 2005 - Amends the Higher Education Act of 1965 to authorize the Secretary of Education to carry out a demonstration program to investigate, develop, and test methods to attempt to ameliorate the cultural mismatch between teachers and the students they teach.
Directs the Secretary to develop a measure of cultural mismatch.
Authorizes program grants to partnerships of local educational agencies and institutions of higher education, or organizations with expertise in multicultural education, for teacher preparation activities under practicum, induction, and in-service phase components.
Authorizes the Secretary to establish up to ten centers of excellence in multicultural education located within universities, colleges, or schools with approved teacher education programs. Allows such centers to form partnerships with specified entities.