Leadership PAC Prohibition Act of 2006 - Amends the Federal Election Campaign Act of 1971 to prohibit a candidate for federal office or federal officeholder from directly or indirectly establishing, financing, maintaining, or controlling any federal or non-federal political committee other than a principal campaign committee of the candidate, an authorized committee, a committee of a political party, or other designated political committee.
Allows a candidate for more than one federal office to designate a separate principal campaign committee for each federal office.