Ponce de Leon Discovery of Florida Quincentennial Commission Act - Establishes the National Commission on the Quincentennial of the discovery of Florida by Ponce de Leon to plan, encourage, coordinate, and conduct the commemoration of the quincentennial (500th anniversary) of the discovery of Florida by the Spanish explorer Ponce de Leon.
Directs the Commission to: (1) plan and develop activities for commemorating the Quincentennial; (2) consult with public and private agencies to organize and participate in Quincentennial activities; and (3) coordinate activities throughout the United States and internationally that relate to the history and influence of such discovery.