Kantishna Hills Renewable Energy Act of 2010 - Directs the Secretary of the Interior to issue permits for a specified microhydro project in nonwilderness areas within the Denali National Park and Preserve in Alaska. Defines "microhydro project" (generally) as a hydroelectric power generating facility with a maximum power generation capability of less than 100 kilowatts.
Directs the Secretary to exchange approximately 18 acres of identified land within the boundary of the Park and Preserve for approximately 18 acres of land owned by Doyon Tourism, Inc.
Requires the land acquired by the Secretary to be administered as part of the Park and Preserve.