Workforce Innovation in Regional Economic Development Act of 2008 - Amends the Workforce Investment Act of 1998 to provide for: (1) preparation and approval of state Workforce Innovation in Regional Economic Development (WIRED) plans for carrying out certain workforce development activities; (2) the integration of workforce development programs and community and economic development programs included as part of an approved plan; and (3) the award of supplementary grants to entities to implement approved WIRED plans and to states to carry out WIRED activities.