Prescription Drug Pricing and Medicaid Fraud Prevention Act of 2005 - Amends title XIX (Medicaid) of the Social Security Act to require the Secretary of Health and Human Services to disclose publicly the average manufacturer prices (AMP) and best prices for prescription drugs.
Requires each drug manufacturer with a rebate agreement in effect to report to the Secretary detailed information (specified by the Secretary) on how the AMP is computed, including assumptions used.