Amends the Internal Revenue Code and the Patient Protection and Affordable Care Act, with respect to the tax credit for the qualifying therapeutic discovery project program, to: (1) extend such credit and credit allocations through 2012; (2) increase the total amount of credits allocable to $2 billion for the 4-year period beginning with 2009; (3) extend from 30 to 90 days the period for review of applications for certification of investments under such program and the time for making payments to applicants; and (4) modify the criteria used by the Secretary of the Treasury for selecting program projects to require the selection of projects that show significant potential (currently, reasonable potential).