Keep Out the IRS Act of 2010 - Prohibits the Internal Revenue Service (IRS) from filling any position, by transfer or any other appointment taking effect on or after the enactment of this Act, if the duties and responsibilities of such position include the implementation, administration, or enforcement of any provision of, or amendment made by, the Patient Protection and Affordable Care Act (PPACA) or the Health Care and Education Reconciliation Act of 2010.