Directs the Secretary to give priority to projects: (1) to improve highway safety on the most dangerous rural two-lane highways on the NHS; (2) carried out on rural highways with respect to which the annual volume of commercial vehicle traffic has increased since the enactment of the North American Free Trade Agreement Implementation Act or is expected to increase after this Act's enactment; (3) carried out on rural highways with high levels of commercial truck traffic; and (4) on highway corridors that will help stimulate regional economic growth and development in rural areas.