Excise Tax Reform and Simplification Act - Amends the Internal Revenue Code (the Code) with respect to the following excise taxes: (1) highway excise taxes, including appropriating to the Highway Trust Fund the gas guzzler tax, and repealing the 4.3-cents-per-gallon General Fund excise tax on diesel fuel used in trains and fuels used in barges operating on the designated inland waterways system; (2) aquatic excise taxes, including establishing the Sport Fish Restoration Trust Fund to be funded by amounts from the Boat Safety Account, repealing the harbor maintenance tax on any exported commercial cargo, and limiting the tax on any fishing rod or pole to ten dollars; (3) aerial excise taxes, including exempting fixed-wing aircraft used for forestry purposes from the tax on air transportation, and exempting certain sightseeing flights from the tax on air transportation; (4) alcoholic beverage excise taxes, including repealing the special occupational taxes on producers and marketers of alcoholic beverages, and repealing the limitation on the cover over of tax to Puerto Rico and the Virgin Islands on distilled spirits; and (5) sport excise taxes, including exempting from the firearms excise tax producers and importers of less than 50 firearms annually, and treating Indian tribal governments as States for purposes of Chapter 35 (Taxes on Wagering) of the Code.